SCHEMBL7576352

SCHEMBL7576352

CC(C)(NC(=O)C(Br)C(C)(C)C)c1ccccc1.CCOC(=O)/C(Cl)=C/c1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
PLA2G1B P04054 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Daimuron SCHEMBL7587643 0.85 MAPT (0.34) MAPT
SCHEMBL5467830 0.82 MAPT (0.37) ALDH1A1MAPTKMT2A
SCHEMBL39177 0.82 MAPT (0.37) ALDH1A1MAPTKMT2A
Tebutam SCHEMBL7576694 0.77 THRB (0.34) MEN1ALDH1A1LMNAPOLBKMT2A
SCHEMBL8897906 0.77 ALDH1A1 (0.34) MEN1ALDH1A1LMNAPLA2G1BPOLB
SCHEMBL8897908 0.77 ALDH1A1 (0.34) MEN1ALDH1A1LMNAPLA2G1BPOLB
SCHEMBL7580161 0.76 CASP3 (0.32) MEN1MAPTKMT2A
SCHEMBL8888819 0.76 MAPT (0.33) ALDH1A1LMNAMAPTKMT2A
SCHEMBL8888827 0.76 MAPT (0.33) ALDH1A1LMNAMAPTKMT2A
Clopyralid SCHEMBL7579092 0.76 KMT2A (0.32) MEN1ALDH1A1LMNAPLA2G1BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT CYP3A4 179/4885MEN1 4274/4885ALDH1A1 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.