Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7578041 | 0.84 | ALDH1A1 (0.60) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL7584783 | 0.84 | LMNA (0.60) | SMN1; SMN2MAPTMEN1KMT2ALMNA | |
| SCHEMBL7583934 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL27992082 | 0.80 | ALDH1A1 (0.61) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL13949527 | 0.79 | MEN1 (0.67) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL5882870 | 0.78 | MAPT (0.44) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL7576573 | 0.78 | RAB9A (0.49) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL2482554 | 0.78 | RAB9A (0.50) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL13240816 | 0.78 | RAB9A (0.50) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL7574185 | 0.77 | HPGD (0.57) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |