Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599743 | 0.88 | CA2 (0.46) | CYP1A2CYP2D6SMN1; SMN2KDM4EPDE4A | |
| SCHEMBL7569870 | 0.87 | TDP1 (0.58) | CNR2CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL7571115 | 0.87 | KMT2A (0.54) | CNR2CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL7573224 | 0.87 | CNR2 (0.58) | CNR2CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL7570560 | 0.84 | KMT2A (0.47) | SMN1; SMN2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL4413263 | 0.83 | CNR2 (0.50) | CNR2ALDH1A1CCR1KMT2AMEN1 | |
| SCHEMBL7570458 | 0.83 | ALDH1A1 (0.55) | CYP1A2CYP2D6SMN1; SMN2KDM4EPDE4A | |
| SCHEMBL7567337 | 0.82 | ELANE (0.48) | CNR2CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL7570455 | 0.80 | ALDH1A1 (0.47) | CYP1A2CYP2D6SMN1; SMN2KDM4EPDE4A | |
| SCHEMBL6136364 | 0.79 | CNR2 (0.58) | CNR2ALDH1A1LMNACCR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |