Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571115 | 0.87 | KMT2A (0.54) | KDM4ECYP2D6SMN1; SMN2CYP1A2PDE4A | |
| SCHEMBL7576943 | 0.87 | CNR2 (0.51) | KDM4ECYP2D6SMN1; SMN2CYP1A2PDE4A | |
| SCHEMBL7573224 | 0.87 | CNR2 (0.58) | TDP1KDM4ECYP2D6SMN1; SMN2CYP1A2 | |
| SCHEMBL7574286 | 0.86 | CNR2 (0.46) | TDP1KDM4ECYP2D6SMN1; SMN2CYP1A2 | |
| SCHEMBL4413648 | 0.83 | TDP1 (0.59) | TDP1KDM4ECYP2D6SMN1; SMN2HTT | |
| SCHEMBL7570458 | 0.83 | ALDH1A1 (0.55) | TDP1KDM4ECYP2D6SMN1; SMN2CYP1A2 | |
| SCHEMBL8599743 | 0.82 | CA2 (0.46) | KDM4ECYP2D6SMN1; SMN2CYP1A2PDE4A | |
| SCHEMBL7567337 | 0.82 | ELANE (0.48) | KDM4ECYP2D6SMN1; SMN2CYP1A2PDE4A | |
| SCHEMBL7576535 | 0.80 | ALDH1A1 (0.49) | TDP1KDM4ESMN1; SMN2RAB9ALMNA | |
| SCHEMBL7570455 | 0.80 | ALDH1A1 (0.47) | TDP1KDM4ECYP2D6SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |