Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573224 | 0.87 | CNR2 (0.58) | HDAC10HDAC6MEN1KMT2AL3MBTL1 | |
| SCHEMBL4565762 | 0.84 | ELANE (0.54) | ELANEMEN1KMT2AL3MBTL1TACR1 | |
| SCHEMBL8599743 | 0.83 | CA2 (0.46) | HDAC10HDAC6MEN1KMT2AL3MBTL1 | |
| SCHEMBL7569870 | 0.82 | TDP1 (0.58) | HDAC10HDAC6KMT2AKDM4ECYP1A2 | |
| SCHEMBL7571115 | 0.82 | KMT2A (0.54) | HDAC10HDAC6HDAC1KMT2AL3MBTL1 | |
| SCHEMBL7576943 | 0.82 | CNR2 (0.51) | HDAC10HDAC6MEN1KMT2AL3MBTL1 | |
| SCHEMBL7574286 | 0.82 | CNR2 (0.46) | HDAC10HDAC6KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7571824 | 0.82 | EPHX2 (0.51) | — | |
| SCHEMBL7571045 | 0.82 | GLS (0.45) | HDAC10HDAC6KDM4ECYP1A2CYP2D6 | |
| SCHEMBL6136552 | 0.80 | MME (0.58) | ELANEMEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |