Diclofop-Methyl

Diclofop-Methyl

SCHEMBL7577102

CCOC(=O)/C(Cl)=C/c1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl.COC(=O)C(C)Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.36
MAPT P10636 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TP53 P04637 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
EPHX2 P34913 1/20 0.32
P2RX3 P56373 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diclofop-Methyl SCHEMBL7581827 0.88 FFAR1 (0.33) FFAR1MAPTL3MBTL1SMN1; SMN2
Bifenox SCHEMBL7579080 0.83 TDP1 (0.55) FFAR1MAPTMEN1KMT2ALMNA
Mecoprop SCHEMBL7575545 0.82 TSHR (0.46) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL5467830 0.81 MAPT (0.37) MAPTKMT2A
SCHEMBL39177 0.81 MAPT (0.37) MAPTKMT2A
Quizalofop SCHEMBL7583244 0.81 TP53 (0.43) MAPTL3MBTL1TP53LMNASMN1; SMN2
Fenoxaprop SCHEMBL7587939 0.81 P2RX3 (0.35) P2RX3
SCHEMBL7579043 0.81 FFAR1 (0.32) FFAR1SMN1; SMN2
Clodinafop SCHEMBL7583811 0.79 L3MBTL1 (0.40) L3MBTL1P2RX3
Propaquizafop SCHEMBL7581012 0.78 TP53 (0.40) MAPTL3MBTL1TP53LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT FFAR1 4198/4885MAPT 1092/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.