SCHEMBL7579043

SCHEMBL7579043

CCOC(=O)/C(Cl)=C/c1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl.C[C@@H](Oc1ccc(Oc2ccc(C#N)cc2F)cc1)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.32
PPARG P37231 3/20 0.31
GPR119 Q8TDV5 1/20 0.30
GAA P10253 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clodinafop SCHEMBL7583811 0.83 L3MBTL1 (0.40) PPARGGAA
Diclofop-Methyl SCHEMBL7577102 0.81 FFAR1 (0.36) FFAR1SMN1; SMN2
Mecoprop SCHEMBL7575545 0.80 TSHR (0.46) PPARGSMN1; SMN2
Fluazifop SCHEMBL7586973 0.80 SCN9A (0.38) GAASMN1; SMN2
Fenoxaprop SCHEMBL7587939 0.78 P2RX3 (0.35) PPARGGAA
Quizalofop SCHEMBL7583244 0.78 TP53 (0.43) PPARGGAASMN1; SMN2
SCHEMBL5467830 0.78 MAPT (0.37)
SCHEMBL39177 0.78 MAPT (0.37)
Ioxynil SCHEMBL7576002 0.77 GPR35 (0.33)
Clodinafop SCHEMBL7578901 0.77 PPARG (0.36) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT FFAR1 4198/4885PPARG 777/4885GPR119 1389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.