Terbuthylazine

Terbuthylazine

SCHEMBL7577314

CCNc1nc(Cl)nc(NC(C)(C)C)n1.CCOC(=O)/C(Cl)=C/c1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 2/20 0.32
MEN1 O00255 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CASP3 P42574 1/20 0.31
KDM4E B2RXH2 1/20 0.30
HTT P42858 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Simazine SCHEMBL7580629 0.95 CASP3 (0.34) KMT2ALMNACASP3KDM4EHTT
Terbutryne SCHEMBL7576055 0.93 LMNA (0.34) TP53L3MBTL1KMT2ALMNAMEN1
Cyanazine SCHEMBL7578899 0.92 PDE4A (0.32)
Terbuthylazine SCHEMBL7582418 0.91 TP53 (0.30) TP53L3MBTL1
Atrazine SCHEMBL7589430 0.90 PKM (0.34) TP53L3MBTL1KMT2ALMNANPSR1
Terbuthylazine SCHEMBL7577433 0.89
Terbuthylazine SCHEMBL7585355 0.88
Simazine SCHEMBL7585122 0.85
Terbutryne SCHEMBL7579570 0.85
Metolachor SCHEMBL7581851 0.84 MAPT (0.34) KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TP53 4303/4885L3MBTL1 2160/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.