SCHEMBL757794

SCHEMBL757794

Cc1ccc(C)c(S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
MAPT P10636 2/20 0.51
POLB P06746 2/20 0.51
HTR6 P50406 5/20 0.48
TDP1 Q9NUW8 1/20 0.48
KMT2A Q03164 2/20 0.47
HTT P42858 2/20 0.46
KDM4E B2RXH2 1/20 0.46
F2 P00734 1/20 0.46
XBP1 P17861 1/20 0.46
SFRP1 Q8N474 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
UBE2N P61088 1/20 0.45
APAF1 O14727 1/20 0.45
GAA P10253 2/20 0.45
GFER P55789 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30963734 1.00 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2MAPTPOLBHTR6
SCHEMBL4403008 0.96 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTPOLBHTR6
SCHEMBL4402282 0.92 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MAPTPOLBHTR6
SCHEMBL13321733 0.90 HTR6 (0.49) ALDH1A1SMN1; SMN2MAPTPOLBHTR6
SCHEMBL11127859 0.88 GAA (0.60) ALDH1A1MAPTTDP1KMT2AHTT
SCHEMBL8057518 0.86 L3MBTL1 (0.58) ALDH1A1SMN1; SMN2MAPTPOLBKMT2A
SCHEMBL13321737 0.85 HTT (0.69) ALDH1A1SMN1; SMN2TDP1HTTKDM4E
SCHEMBL13321731 0.85 HTT (0.69) ALDH1A1SMN1; SMN2TDP1HTTKDM4E
SCHEMBL11599302 0.85 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2MAPTPOLBHTR6
SCHEMBL2487383 0.85 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2MAPTPOLBHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9650330-B2 Process for the synthesis of aryl sulfones COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-05-16 US claimed
US-20160304447-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-10-20 US claimed
US-9650330-B2 Process for the synthesis of aryl sulfones COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-05-16 US disclosed
US-9650330-B2 Process for the synthesis of aryl sulfones COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-05-16 US disclosed
US-9650330-B2 Process for the synthesis of aryl sulfones COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-05-16 US disclosed
US-20160304447-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-10-20 US disclosed
US-20160304447-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-10-20 US disclosed
US-20160304447-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-10-20 US disclosed
WO-2015087352-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-06-18 WO disclosed
WO-2015087352-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-06-18 WO disclosed
US-20120322973-A1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-20 US disclosed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
US-20090274943-A1 CROSSLINKED POLYMER ELECTROLYTE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-05 US disclosed
US-20090233142-A2 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-17 US disclosed
US-20090110995-A1 POLYMER HAVING OXYCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20090110994-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20080309860-A1 Optical Film, Optical Compensation Film, Polarizing Plate, Liquid Crystal Display Unit and Self Luminous Display Unit FUJIFILM CORPORATION (JP) 2008-12-18 US disclosed
US-20080309860-A1 Optical Film, Optical Compensation Film, Polarizing Plate, Liquid Crystal Display Unit and Self Luminous Display Unit FUJIFILM CORPORATION (JP) 2008-12-18 US disclosed
US-20070218335-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF KAO CORPORATION (JP) 2007-09-20 US disclosed
US-4103015-A TRICYCLIC THIOXANTHONE-10,10-DIOXIDES BURROUGHS WELLCOME CO. (US) 1978-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304447-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES ARSA, TPST2, STS ALDH1A1 552/4885SMN1; SMN2 1701/4885MAPT 2353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.