Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mesotrione SCHEMBL7578240 | 0.95 | HPD (0.53) | HPDLMNAMAPK1TDP1CACNA1B | |
| Sulcotrione SCHEMBL7575267 | 0.90 | HPD (0.41) | HPDLMNAMAPK1TDP1CACNA1B | |
| Sulcotrione SCHEMBL7588689 | 0.89 | HPD (0.40) | HPDLMNAMAPK1CACNA1BNR1I2 | |
| Sulcotrione SCHEMBL7584714 | 0.87 | HPD (0.39) | HPDCACNA1BNR1I2FLT1FLT4 | |
| Mesotrione SCHEMBL7578069 | 0.85 | HPD (0.43) | HPDFLT1FLT4KDRIDO1 | |
| Mesotrione SCHEMBL7590430 | 0.84 | HPD (0.42) | HPDIDO1TDO2GABRPGABRD | |
| Mesotrione SCHEMBL7577203 | 0.83 | HPD (0.41) | HPDFLT1FLT4KDRIDO1 | |
| Nitisinone SCHEMBL8423048 | 0.83 | HPD (0.75) | HPDLMNAMAPK1CACNA1BNR1I2 | |
| Mesotrione SCHEMBL7576149 | 0.79 | HPD (0.36) | HPDMAPT | |
| Mesotrione SCHEMBL1984911 | 0.78 | HPD (0.58) | HPDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020004457-A1 | Herbicidal composition | SYNGENTA PARTICIPATIONS AG (CH) | 2002-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004457-A1 | Herbicidal composition | PPOX, ALAD, DDT | HPD 7/4885LMNA 3881/4885MAPK1 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.