Sulcotrione

Sulcotrione

SCHEMBL7584714

CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1.C[S+](C)C.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPD P32754 1/20 0.39
NR1I2 O75469 1/20 0.31
CACNA1B Q00975 1/20 0.31
FLT1 P17948 1/20 0.31
FLT4 P35916 1/20 0.31
KDR P35968 1/20 0.31
P2RX7 Q99572 1/20 0.31
SMO Q99835 1/20 0.30
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mesotrione SCHEMBL7577203 0.96 HPD (0.41) HPDFLT1FLT4KDRIDO1
Sulcotrione SCHEMBL7575267 0.94 HPD (0.41) HPDNR1I2CACNA1BFLT1FLT4
Mesotrione SCHEMBL7578069 0.90 HPD (0.43) HPDFLT1FLT4KDRP2RX7
Sulcotrione SCHEMBL7577959 0.87 HPD (0.51) HPDNR1I2CACNA1BFLT1FLT4
Glyphosate SCHEMBL7587855 0.85 GABRA2 (0.39)
Mesotrione SCHEMBL7578240 0.83 HPD (0.53) HPDNR1I2CACNA1BFLT1FLT4
Sulcotrione SCHEMBL7588689 0.83 HPD (0.40) HPDNR1I2CACNA1B
Acifluorfen SCHEMBL7579292 0.80 TDP1 (0.51) HPDNR1I2CACNA1BFLT1FLT4
Mesotrione SCHEMBL7590430 0.80 HPD (0.42) HPDIDO1TDO2
Isoxaflutole SCHEMBL7586601 0.79 THRB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT HPD 7/4885NR1I2 2507/4885CACNA1B 2521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.