Mesotrione

Mesotrione

SCHEMBL7577203

CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c([N+](=O)[O-])c1.C[S+](C)C.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HPD P32754 1/20 0.41
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31
CCR1 P32246 1/20 0.31
FLT1 P17948 1/20 0.31
FLT4 P35916 1/20 0.31
KDR P35968 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulcotrione SCHEMBL7584714 0.96 HPD (0.39) HPDIDO1TDO2FLT1FLT4
Mesotrione SCHEMBL7578069 0.94 HPD (0.43) HPDIDO1TDO2CCR1FLT1
Sulcotrione SCHEMBL7575267 0.90 HPD (0.41) HPDIDO1TDO2CCR1FLT1
Mesotrione SCHEMBL7578240 0.87 HPD (0.53) HPDIDO1TDO2FLT1FLT4
Glyphosate SCHEMBL7587855 0.85 GABRA2 (0.39) CCR1
Sulcotrione SCHEMBL7577959 0.83 HPD (0.51) HPDIDO1TDO2FLT1FLT4
Mesotrione SCHEMBL7590430 0.83 HPD (0.42) HPDIDO1TDO2
Mesotrione SCHEMBL7576656 0.80 HPD (0.32) HPD
Acifluorfen SCHEMBL7585981 0.80 TDP1 (0.51) HPDFLT1FLT4KDR
Sulcotrione SCHEMBL7588689 0.80 HPD (0.40) HPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT HPD 7/4885IDO1 373/4885TDO2 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.