Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493834 | 0.86 | KMT2A (0.65) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL8797276 | 0.74 | KMT2A (0.50) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL28572242 | 0.73 | NPSR1 (0.60) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL5232736 | 0.73 | RAB9A (0.53) | KMT2ARAB9ANPC1KDM4EMAPT | |
| SCHEMBL8800517 | 0.72 | KMT2A (0.67) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL7501376 | 0.71 | KMT2A (0.63) | L3MBTL1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL7572668 | 0.71 | KMT2A (0.50) | L3MBTL1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL29677294 | 0.71 | ALDH1A1 (0.54) | KMT2AKDM4EHTTPOLBALDH1A1 | |
| SCHEMBL93382 | 0.71 | ALDH1A1 (0.54) | KMT2AKDM4EHTTPOLBALDH1A1 | |
| SCHEMBL16674460 | 0.70 | KMT2A (0.63) | L3MBTL1KMT2ARAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915876-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997049707-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-31 | — | — | WO | disclosed |