Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL1897914 | 0.98 | CA1 (0.50) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL1518007 | 0.98 | CA1 (0.50) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL1301472 | 0.98 | CA1 (0.46) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL1899057 | 0.98 | CA1 (0.46) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL23611029 | 0.95 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL161673 | 0.95 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL377275 | 0.95 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL21638309 | 0.95 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL20593979 | 0.95 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL1457846 | 0.95 | CA1 (0.48) | CA1BBOX1GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014020131-A1 | ANTIMICROBIAL COMPOSITION, DEVICE COMPRISING IT AND PROCESS | CRAWFORD HEALTHCARE LTD (GB) | 2014-02-06 | — | — | WO | claimed |
| WO-2014020133-A2 | PROCESS AND DEVICE | CRAWFORD HEALTHCARE LTD (GB) | 2014-02-06 | — | — | WO | claimed |
| US-20230381144-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PAIN | SYNVENTA LLC (US) | 2023-11-30 | — | — | US | disclosed |
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | Exciva GmbH (DE) | 2022-10-25 | — | — | US | disclosed |
| WO-2021102330-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PAIN | SYNVENTA LLC (US) | 2021-05-27 | — | — | WO | disclosed |
| US-20210155597-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PAIN | SYNVENTA LLC | 2021-05-27 | — | — | US | disclosed |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | VEPACHEDU SREENIVASARAO (US) | 2020-08-20 | — | — | US | disclosed |
| EP-3618819-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-11 | — | — | EP | disclosed |
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-05 | — | — | US | disclosed |
| US-10392423-B2 | Peptide-based inhibitors of MLL/SET1 family core complexes | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2019-08-27 | — | — | US | disclosed |
| WO-2018204713-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | EXCIVA UG (HAFTUNGSBESCHRÄNKT) (DE) | 2018-11-08 | — | — | WO | disclosed |
| EP-2286238-A1 | METHODS OF DISTINGUISHING BETWEEN GLUTAMINE FORMED BY CATAPLEROSIS OR PROTEOLYSIS | Biocant - Associação De Transferência De Tecnologia (PT) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009141619-A1 | METHODS OF DISTINGUISHING BETWEEN GLUTAMINE FORMED BY CATAPLEROSIS OR PROTEOLYSIS | Biocant - Associação De Transferência De Tecnologia (PT) | 2009-11-26 | — | — | WO | disclosed |
| CN-1215835-C | Ketone derivatives and medical use thereof | TORAY INDUSTRIES (JP) | 2005-08-24 | — | — | CN | disclosed |
| US-20040053385-A1 | Crystal structure | ASTEX TECHNOLOGY LIMITED (GB) | 2004-03-18 | — | — | US | disclosed |
| EP-1373482-A2 | CRYSTALS OF KETOPANTOATE HYDROXYMETHYLTRANSFERASE | Astex Technology Limited (GB) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079460-A2 | CRYSTALS OF KETOPANTOATE HYDROXYMETHYL TRANSFERASE | ASTEX TECHNOLOGY LIMITED (GB) | 2002-10-10 | — | — | WO | disclosed |
| US-6030625-A | Bordetella pertussis and Bordetella parapertussis strains | INSTITUT PASTEUR (FR) | 2000-02-29 | — | — | US | disclosed |
| US-5985286-A | ADENYL CYCLASE-HEMOLYSIN (AC-HLY) PROTEIN, | INSTITUT PASTEUR (FR) | 1999-11-16 | — | — | US | disclosed |
| EP-0443560-A2 | HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | HTR2A, HTR2C, CYP3A43 | CA1 2142/4885BBOX1 510/4885GRM8 1483/4885 |
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2A, HTR2C, CYP3A43 | CA1 2142/4885BBOX1 510/4885GRM8 1483/4885 |
| US-20230381144-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PAIN | TRPV1, OPRL1, ADRA2C | CA1 2203/4885BBOX1 1039/4885GRM8 859/4885 |
| US-10392423-B2 | Peptide-based inhibitors of MLL/SET1 family core complexes | MLLT1, RBX1, SETDB1 | CA1 1866/4885BBOX1 3102/4885GRM8 1908/4885 |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2C, HTR2A, HTR3A | CA1 1799/4885BBOX1 783/4885GRM8 195/4885 |
| US-20210155597-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PAIN | TRPV1, OPRL1, OPRK1 | CA1 1729/4885BBOX1 1754/4885GRM8 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.