Flumioxazin

Flumioxazin

SCHEMBL7579265

C#CCN1C(=O)COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21.Cc1cc(Cl)ccc1OC(C)C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
ALOX12 P18054 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GRM7 Q14831 1/20 0.38
GRM4 Q14833 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumioxazin SCHEMBL7581482 0.88 KMO (0.36) TSHRHTR2AHTR2CHTR2B
Flumioxazin SCHEMBL7579220 0.82 P2RX3 (0.33) GRM7GRM4
Flumioxazin SCHEMBL7579546 0.82
Flumioxazin SCHEMBL7589028 0.82 LTA4H (0.33)
Flumioxazin SCHEMBL7588749 0.81 TP53 (0.41) LMNAMAPTSMN1; SMN2NPSR1
Flumioxazin SCHEMBL7587028 0.81
Flumioxazin SCHEMBL39699 0.79 GRM1 (0.37) GRM7GRM4
Flumioxazin SCHEMBL29539500 0.79 GRM1 (0.37) GRM7GRM4
Flumioxazin SCHEMBL29088353 0.78 GRM1 (0.37) GRM7GRM4
Flumioxazin SCHEMBL19641848 0.78 GRM1 (0.39) GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TSHR 3055/4885HTR2A 4430/4885HTR2C 3919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.