SCHEMBL7579792

SCHEMBL7579792

CCNC(=O)C(C)OC(=O)Nc1ccccc1.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 2/20 0.37
MAPT P10636 6/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
GABRA2 P47869 5/20 0.35
GABRB2 P47870 5/20 0.35
GABRP O00591 4/20 0.35
GABRD O14764 4/20 0.35
GABRA1 P14867 4/20 0.35
GABRB1 P18505 4/20 0.35
GABRG2 P18507 4/20 0.35
GABRB3 P28472 4/20 0.35
GABRA5 P31644 4/20 0.35
GABRA3 P34903 4/20 0.35
GABRA4 P48169 4/20 0.35
GABRE P78334 4/20 0.35
GABRA6 Q16445 4/20 0.35
GABRG1 Q8N1C3 4/20 0.35
GABRG3 Q99928 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Desmedipham SCHEMBL7584402 0.80 GABRP (0.39) ALDH1A1RAB9AMAPTMEN1KMT2A
Isoproturon SCHEMBL7584700 0.75 BACE1 (0.39) ALDH1A1RAB9AMAPTGABRA2GABRB2
Propanil SCHEMBL7587518 0.75 CYP3A4 (0.47) ALDH1A1RAB9AMAPTMEN1KMT2A
SCHEMBL39558 0.75 ALDH1A1 (0.48) ALDH1A1GABRA2GABRB2GABRPGABRD
SCHEMBL7582320 0.74 CYP3A4 (0.39) ALDH1A1MAPTMEN1KMT2AGABRA2
Acifluorfen SCHEMBL7580482 0.74 MEN1 (0.64) ALDH1A1MAPTMEN1KMT2APOLB
Fluometuron SCHEMBL7582543 0.74 TP53 (0.53) RAB9AMAPTMEN1KMT2AGABRA2
Phenmedipham SCHEMBL7580294 0.74 ALDH1A1 (0.49) ALDH1A1RAB9AMAPTMEN1KMT2A
Oxyfluorfen SCHEMBL7584610 0.74 MEN1 (0.50) ALDH1A1MAPTMEN1KMT2APOLB
Tebutam SCHEMBL7584123 0.73 TRPM8 (0.42) ALDH1A1MAPTGABRA2GABRB2GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT ALDH1A1 812/4885RAB9A 1914/4885MAPT 1092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.