Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12768024 | 0.98 | FFAR4 (0.61) | CA1CA2CA4CA7CA9 | |
| SCHEMBL5956006 | 0.92 | KEAP1 (0.58) | CA1CA2CA4CA7CA9 | |
| SCHEMBL7580401 | 0.92 | CA1 (0.70) | CA1CA2CA4CA7CA9 | |
| SCHEMBL5955235 | 0.86 | CYP2C9 (0.59) | FFAR4KMT2ATP53LMNAMAPT | |
| SCHEMBL7574222 | 0.84 | APP (0.73) | CA1CA2CA4CA7CA9 | |
| SCHEMBL7588784 | 0.83 | ALDH1A1 (0.59) | CA1CA2CA4CA7CA9 | |
| SCHEMBL7589428 | 0.83 | FFAR4 (0.67) | FFAR4KMT2ATP53LMNAMAPT | |
| SCHEMBL7579963 | 0.81 | METAP2 (0.69) | CA1CA2CA4CA7CA9 | |
| SCHEMBL28610415 | 0.81 | KEAP1 (0.54) | CA1CA2CA4CA7CA9 | |
| SCHEMBL2008393 | 0.81 | MAPT (0.60) | FFAR4KMT2ATP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |