Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595414 | 0.85 | ALDH1A1 (0.70) | ALDH1A1LMNACYP2C9CYP2C19USP2 | |
| SCHEMBL7594942 | 0.85 | KEAP1 (0.62) | KEAP1NFE2L2CA2CA1FFAR4 | |
| SCHEMBL5955952 | 0.85 | MAPT (0.55) | ALDH1A1LMNACYP2C9CYP2C19USP2 | |
| SCHEMBL5956006 | 0.84 | KEAP1 (0.58) | ALDH1A1LMNACYP2C9CYP2C19USP2 | |
| SCHEMBL7580401 | 0.83 | CA1 (0.70) | ALDH1A1LMNACYP2C9CYP2C19USP2 | |
| SCHEMBL7579899 | 0.83 | CA1 (0.60) | LMNAPOLBMAPTKEAP1NFE2L2 | |
| SCHEMBL8695450 | 0.83 | KMT2A (0.61) | ALDH1A1LMNACYP2C9CYP2C19USP2 | |
| SCHEMBL3072539 | 0.82 | LMNA (0.70) | ALDH1A1LMNACYP2C9CYP2C19USP2 | |
| SCHEMBL2367811 | 0.81 | APP (0.62) | ALDH1A1LMNACYP2C9CYP2C19USP2 | |
| SCHEMBL5956125 | 0.81 | ALDH1A1 (0.59) | ALDH1A1LMNACYP2C9CYP2C19USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |