Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | METAP2 | P50579 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595414 | 0.85 | ALDH1A1 (0.70) | FFAR4POLBKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL7594942 | 0.85 | KEAP1 (0.62) | FFAR4TSHRKEAP1NFE2L2MEN1 | |
| SCHEMBL12768024 | 0.84 | FFAR4 (0.61) | FFAR4TP53KEAP1NFE2L2MEN1 | |
| SCHEMBL7579899 | 0.83 | CA1 (0.60) | FFAR4TP53POLBKEAP1NFE2L2 | |
| SCHEMBL13875339 | 0.82 | ALDH1A1 (0.71) | FFAR4TSHRKEAP1NFE2L2MEN1 | |
| SCHEMBL7595505 | 0.81 | KEAP1 (0.59) | FFAR4TSHRKEAP1NFE2L2MEN1 | |
| SCHEMBL7591229 | 0.81 | CA12 (0.50) | FFAR4TSHRTP53KEAP1NFE2L2 | |
| SCHEMBL29402285 | 0.81 | ALDH1A1 (0.69) | FFAR4TSHRKEAP1METAP2MEN1 | |
| SCHEMBL7589780 | 0.81 | ALDH1A1 (0.69) | FFAR4TSHRKEAP1METAP2MEN1 | |
| SCHEMBL5956006 | 0.81 | KEAP1 (0.58) | FFAR4TP53POLBKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |