Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404689 | 0.81 | TAAR1 (0.63) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL8714613 | 0.79 | — | — | |
| SCHEMBL3302008 | 0.79 | PNMT (0.68) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL17552713 | 0.78 | PNMT (0.43) | PNMTTAAR1IDO1TSHRCYP1A2 | |
| SCHEMBL42705 | 0.77 | PNMT (1.00) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL17552708 | 0.77 | CYP3A4 (0.40) | PNMTTAAR1IDO1CYP3A4CYP2A6 | |
| SCHEMBL283449 | 0.77 | PNMT (0.65) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL17552715 | 0.76 | TAAR1 (0.38) | PNMTTAAR1IDO1ALDH1A1CYP2A13 | |
| SCHEMBL1145379 | 0.75 | IDO1 (0.65) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL1547863 | 0.75 | PNMT (0.62) | PNMTTAAR1IDO1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0130338-B1 | RESIST STRUCTURE AND PROCESSES FOR MAKING AND PATTERNING IT | International Business Machines Corporation (US) | 1988-05-04 | — | — | EP | claimed |
| EP-0130338-A2 | Resist structure and processes for making and patterning it | International Business Machines Corporation (US) | 1985-01-09 | — | — | EP | claimed |
| US-4464460-A | Process for making an imaged oxygen-reactive ion etch barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1984-08-07 | — | — | US | claimed |
| EP-4698583-A1 | PREPARATION OF AN ALKOXY- OR HYDROXY-TERMINATED POLY(PHENYLMETHYL) SILOXANE | Dow Silicones Corporation (US) | 2026-02-25 | — | — | EP | disclosed |
| EP-3371248-B1 | CONTINUOUS METHOD FOR REACTIONS WITH FINE-PARTICULATE ALKALI METAL DISPERSIONS | CHT Germany GmbH (DE) | 2025-03-26 | — | — | EP | disclosed |
| WO-2024220241-A1 | PREPARATION OF AN ALKOXY- OR HYDROXY-TERMINATED POLY(PHENYLMETHYL) SILOXANE | DOW SILICONES CORPORATION (US) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024173050-A1 | PREPARATION OF AN ALKOXY-TERMINATED POLY(PHENYLMETHYL) SILOXANE | DOW SILICONES CORPORATION (US) | 2024-08-22 | — | — | WO | disclosed |
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | VOCO GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| CN-108431092-B | Continuous process for reacting with particulate alkali metal dispersions | CHT R.拜特利希有限公司 | 2021-03-02 | — | — | CN | disclosed |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | disclosed |
| US-10640630-B2 | Elastomeric composites containing modified fillers and functionalized elastomers | CABOT CORPORATION (US) | 2020-05-05 | — | — | US | disclosed |
| US-4917980-A | Photoresponsive imaging members with hole transporting polysilylene ceramers | XEROX CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| US-4826892-A | CONDENSATION POLYMERIZATION OF DICHLORODIMETHYLSILANE AND DICHLOROMETHYLPHENYLSILANE | TEIJIN LIMITED (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4822703-A | Photoresponsive imaging members with polygermanes | XEROX CORPORATION (US) | 1989-04-18 | — | — | US | disclosed |
| US-4743411-A | Process for producing shaped silicon carbide article from a polycarbosilastyrene copolymer | TEIJIN LIMITED (JP) | 1988-05-10 | — | — | US | disclosed |
| US-4717770-A | CYCLOHEXANONE OXIME, ZEOLITES, SURFACE TREATMENT WITH ORGANOSILICON OR ORGANOGERMANIUM COMPOUNDS | SUMITOMO CHEMICAL CO., LTD. (JP) | 1988-01-05 | — | — | US | disclosed |
| EP-0236092-A2 | Process for producing e-caprolactam | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-09 | — | — | EP | disclosed |
| EP-0130338-A2 | Resist structure and processes for making and patterning it | International Business Machines Corporation (US) | 1985-01-09 | — | — | EP | disclosed |
| US-4464460-A | Process for making an imaged oxygen-reactive ion etch barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |
| US-4151327-A | WATER AND OIL REPELLANT, DIMENSIONAL STABILITY, CLARITY OR OPACITY | LAWTON WILLIAM R | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | NCAPH, RCC1, NCAPD2 | PNMT 4461/4885TAAR1 2152/4885IDO1 3791/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | PNMT 4461/4885TAAR1 2152/4885IDO1 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.