Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29797968 | 1.00 | MAOA (0.61) | MAOAMAOBCES1CYP2A6PARP1 | |
| Hydrochloric Acid SCHEMBL28482741 | 0.98 | MAOA (0.59) | MAOAMAOBCES1CYP2A6PARP1 | |
| Fluoride SCHEMBL8592140 | 0.79 | MAOA (0.95) | MAOAMAOBCES1ALDH1A1KDM4E | |
| SCHEMBL3733365 | 0.78 | ALOX15 (0.55) | MAOAMAOBCES1ALDH1A1KDM4E | |
| SCHEMBL6903786 | 0.76 | MAOA (1.00) | MAOAMAOBCES1ALDH1A1KDM4E | |
| SCHEMBL6353583 | 0.76 | MAOA (1.00) | MAOAMAOBCES1ALDH1A1KDM4E | |
| SCHEMBL29448271 | 0.76 | MAOA (1.00) | MAOAMAOBCES1ALDH1A1KDM4E | |
| SCHEMBL22284 | 0.76 | MAOA (1.00) | MAOAMAOBCES1ALDH1A1KDM4E | |
| SCHEMBL11522370 | 0.76 | MAOA (1.00) | MAOAMAOBCES1ALDH1A1KDM4E | |
| SCHEMBL13932277 | 0.76 | CES1 (0.41) | MAOAMAOBCES1CYP2A6PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350408-A | Dihydro-isocoumarin compound and preparation method and application thereof | 河南中医药大学 | 2025-01-24 | — | — | CN | claimed |
| CN-119097623-A | Application of chrysogenum fermentation product in preparation of medicines for preventing or treating drug-resistant bacterial infection by extracting dihydro-isocoumarin derivative | 苏州万维生命科学技术有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-118619913-A | Synthesis method of dihydro-isocoumarin compound | 浙江九洲药业股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-118344324-A | Isochroman-1-ketone compound, preparation method and application thereof | 江苏海洋大学 | 2024-07-16 | — | — | CN | claimed |
| CN-118324647-A | Preparation method and application of dye intermediate for anti-irritation hair dyeing | 浙江工业大学 | 2024-07-12 | — | — | CN | claimed |
| CN-117599043-A | Application of dihydro-isocoumarin and derivatives thereof in preparation of medicines for treating orthopedic diseases | 中国人民解放军联勤保障部队第九二〇医院 | 2024-02-27 | — | — | CN | claimed |
| CN-115611693-B | Method for catalytic synthesis of isochroman-1-one or aromatic ketone compound | 常州大学 | 2023-11-28 | — | — | CN | claimed |
| CN-117024423-A | Synthetic method of 3, 4-dihydro-isocoumarin-beta-carboline hybrid and analogue thereof | 伊犁师范大学 | 2023-11-10 | — | — | CN | claimed |
| CN-114146097-B | Application of periplaneta americana extract and/or monomer in preparation of tumor microenvironment M2 polarization inhibition drugs | 大理大学 | 2023-06-23 | — | — | CN | claimed |
| CN-115611693-A | Method for catalytically synthesizing isochroman-1-ketone or aromatic ketone compounds | 常州大学 | 2023-01-17 | — | — | CN | claimed |
| US-6057352-A | CONTROLLING PLANT DISEASES CAUSED BY FUNGAL PLANT PATHOGENS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | claimed |
| WO-1998023155-A1 | ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-04 | — | — | WO | claimed |
| EP-0836384-A1 | ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-22 | — | — | EP | claimed |
| EP-0825988-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-04 | — | — | EP | claimed |
| EP-0825992-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-04 | — | — | EP | claimed |
| WO-1997000612-A1 | ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-09 | — | — | WO | claimed |
| WO-1996036616-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-11-21 | — | — | WO | claimed |
| WO-1996036633-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-11-21 | — | — | WO | claimed |
| WO-1996036229-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-11-21 | — | — | WO | claimed |
| US-4650881-A | ONE POT | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1987-03-17 | — | — | US | claimed |