Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9246632 | 0.97 | FABP4 (0.31) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL3224857 | 0.97 | CA1 (0.32) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL11436441 | 0.83 | LMNA (0.34) | ALDH1A1KDM4EMEN1HPGDCRHBP | |
| SCHEMBL3341069 | 0.83 | CA1 (0.32) | ALDH1A1LMNAMAPK1PHLPP2 | |
| SCHEMBL985182 | 0.76 | KDM4E (0.41) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL9246637 | 0.75 | KDM4E (0.40) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL3912717 | 0.75 | KDM4E (0.40) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL758181 | 0.75 | KDM4E (0.40) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL3442546 | 0.73 | CA1 (0.38) | FABP4ALDH1A1KDM4EHPGDHSD17B10 | |
| Lithium Ion SCHEMBL2469320 | 0.71 | ALDH1A1 (0.30) | ALDH1A1KMT2AHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368404-A1 | SULFOISOPHTHALIC ACID SOLUTION AND PROCESS THEREWITH | E. I. du Pont de Nemours and Company (US) | 2003-12-10 | — | — | EP | claimed |
| US-20020169273-A1 | Sulfoisophthalic acid solution and process therewith | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-11-14 | — | — | US | claimed |
| US-6479619-B1 | PRODUCING A PARTIALLY ESTERIFIED ALKALI METAL SULFOISOPHTHALIC ACID IN A GLYCOL; CAN BE MADE IMMEDIATELY PRIOR TO USE; COPOLYMERIZING WITH TEREPHTHALIC ACID AND A GLYCOL TO FORM A POLYESTER | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-11-12 | — | — | US | claimed |
| WO-2002074834-A1 | SULFOISOPHTHALIC ACID SOLUTION AND PROCESS THEREWITH | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-26 | — | — | WO | claimed |
| EP-2264543-B1 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | XEROX CORP (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2264543-A1 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | Xerox Corporation (US) | 2010-12-22 | — | — | EP | disclosed |
| US-7312011-B2 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | XEROX CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1684124-A2 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | Xerox Corporation (US) | 2006-07-26 | — | — | EP | disclosed |
| US-20060160010-A1 | Super low melt and ultra low melt toners containing crystalline sulfonated polyester | XEROX CORPORATION (US) | 2006-07-20 | — | — | US | disclosed |
| US-5407981-A | Reacting ester of dibasic acid, short chain diol,long chain polyglycol, alkali salt of dialkylsulfoisophthalate, stabilizers and alkali salt of phenol; for extrusion, blow molding | CHEIL SYNTHETICS INC. (KR) | 1995-04-18 | — | — | US | disclosed |
| EP-0605260-A1 | Preparation of polyether ester elastomers having high melt viscosities and crystallization | CHEIL SYNTHETICS INC. (KR) | 1994-07-06 | — | — | EP | disclosed |