Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.32 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.32 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9246632 | 0.97 | FABP4 (0.31) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| Lithium Ion SCHEMBL758180 | 0.97 | FABP4 (0.31) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL11436441 | 0.87 | LMNA (0.34) | CA1CA2CA4ALDH1A1KDM4E | |
| SCHEMBL3341069 | 0.87 | CA1 (0.32) | CA1CA2CA4ALDH1A1LMNA | |
| SCHEMBL3442546 | 0.77 | CA1 (0.38) | CA1CA2FABP4ALDH1A1KDM4E | |
| SCHEMBL985182 | 0.76 | KDM4E (0.41) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL3912717 | 0.75 | KDM4E (0.40) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL9246637 | 0.75 | KDM4E (0.40) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL758181 | 0.75 | KDM4E (0.40) | FABP4ALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL9403857 | 0.72 | CA1 (0.33) | CA1CA2CA4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368404-A1 | SULFOISOPHTHALIC ACID SOLUTION AND PROCESS THEREWITH | E. I. du Pont de Nemours and Company (US) | 2003-12-10 | — | — | EP | claimed |
| US-20020169273-A1 | Sulfoisophthalic acid solution and process therewith | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-11-14 | — | — | US | claimed |
| US-6479619-B1 | PRODUCING A PARTIALLY ESTERIFIED ALKALI METAL SULFOISOPHTHALIC ACID IN A GLYCOL; CAN BE MADE IMMEDIATELY PRIOR TO USE; COPOLYMERIZING WITH TEREPHTHALIC ACID AND A GLYCOL TO FORM A POLYESTER | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-11-12 | — | — | US | claimed |
| WO-2002074834-A1 | SULFOISOPHTHALIC ACID SOLUTION AND PROCESS THEREWITH | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-26 | — | — | WO | claimed |
| EP-0547106-B1 | IMPROVED SOIL RELEASE AGENTS FOR GRANULAR LAUNDRY DETERGENTS | PROCTER & GAMBLE (US) | 1995-12-27 | — | — | EP | claimed |
| US-4104262-A | LACQUER BINDING AGENTS | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | claimed |
| JP-4114020-A | — | — | None | — | — | JP | disclosed |
| CN-115746176-A | Single ion polymer, preparation method and application thereof | 蓝京新能源(嘉兴)有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115536822-A | Dacron reduction-free cleaning agent and preparation method thereof | 中山市好本意新材料有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-111417881-B | Delay device | 3M创新有限公司 | 2022-06-28 | — | — | CN | disclosed |
| US-20200399823-A1 | METHOD OF MANUFACTURING ANTI-SOILING CARPET, AND ANTI-SOILING CARPET | NICCA U.S.A., INC. | 2020-12-24 | — | — | US | disclosed |
| CN-111417881-A | Delay device | 3M创新有限公司 | 2020-07-14 | — | — | CN | disclosed |
| US-8399168-B2 | Method for producing toner, two-component developer, developing device and image forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2013-03-19 | — | — | US | disclosed |
| EP-0105016-A1 | Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4427557-A | POLYESTERETHER FROM ETHYLENE GLYCOL, POLYOXYETHYLENE GLYCOL, ARYLDICARBOXY ACID, AND SULFOARYLDICARBOXY/ ACID | ICI AMERICAS INC. (US) | 1984-01-24 | — | — | US | disclosed |
| US-4424337-A | Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0066944-A1 | Anionic textile treating composition | ICI AMERICAS INC. (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4150946-A | ABRASION RESISTANT TEXTILES | RHONE-POULENC INDUSTRIES (FR) | 1979-04-24 | — | — | US | disclosed |
| US-4110284-A | Polyurethane latexes from sulfonate prepolymer, aqueous chain extension process, and coated support | RHONE-PROGIL (FR) | 1978-08-29 | — | — | US | disclosed |
| US-4104262-A | LACQUER BINDING AGENTS | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |