Quizalofop

Quizalofop

SCHEMBL7581964

CC(Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1)C(=O)O.COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.62
LMNA P02545 6/20 0.51
MAPT P10636 6/20 0.51
ALDH1A1 P00352 5/20 0.51
HPGD P15428 5/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
TP53 P04637 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
ALOX15 P16050 1/20 0.51
NFKB1 P19838 1/20 0.51
HIF1A Q16665 1/20 0.51
GMNN O75496 1/20 0.51
APEX1 P27695 1/20 0.51
PMP22 Q01453 1/20 0.51
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
TTR P02766 1/20 0.40
PPOX P50336 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propaquizafop SCHEMBL7578027 0.87 TDP1 (0.53) TDP1LMNAMAPTALDH1A1HPGD
Quizalofop SCHEMBL7589679 0.87 TDP1 (0.60) TDP1LMNAMAPTALDH1A1HPGD
Fluazifop SCHEMBL7576720 0.84 TDP1 (0.60) TDP1LMNAMAPTALDH1A1HPGD
Fenoxaprop SCHEMBL7581910 0.84 TDP1 (0.62) TDP1LMNAMAPTALDH1A1HPGD
Quizalofop SCHEMBL7580854 0.83 TDP1 (0.47) TDP1LMNAMAPTALDH1A1HPGD
Diclofop-Methyl SCHEMBL7583912 0.82 TDP1 (0.79) TDP1LMNAMAPTALDH1A1HPGD
Quizalofop SCHEMBL7580307 0.81 MEN1 (0.47) TDP1LMNAMAPTALDH1A1HPGD
Quizalofop SCHEMBL1010164 0.80 ALDH1A1 (0.72) TDP1LMNAMAPTALDH1A1HPGD
Quizalofop SCHEMBL111413 0.80 ALDH1A1 (0.72) TDP1LMNAMAPTALDH1A1HPGD
Quizalofop SCHEMBL19210826 0.80 ALDH1A1 (0.72) TDP1LMNAMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885LMNA 3881/4885MAPT 1092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.