Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 9/20 | 0.39 |
| ▸ | DRD3 | P35462 | 9/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587091 | 0.87 | P2RX7 (0.41) | P2RX7DPP4DRD2DRD3 | |
| SCHEMBL7589899 | 0.86 | NAAA (0.45) | P2RX7DPP4DRD2DRD3NAAA | |
| SCHEMBL7590018 | 0.85 | DRD2 (0.41) | P2RX7DRD2DRD3PTPRCPTPN1 | |
| SCHEMBL7585483 | 0.84 | P2RX7 (0.41) | P2RX7DPP4DRD2DRD3FFAR2 | |
| SCHEMBL7583788 | 0.84 | P2RX7 (0.41) | P2RX7DPP4DRD2DRD3 | |
| SCHEMBL7582945 | 0.84 | P2RX7 (0.41) | P2RX7DPP4DRD2DRD3FFAR2 | |
| SCHEMBL27419636 | 0.83 | P2RX7 (0.40) | P2RX7DPP4DRD2DRD3 | |
| SCHEMBL7583781 | 0.82 | P2RX7 (0.51) | P2RX7FFAR2MAOA | |
| SCHEMBL7583792 | 0.80 | DRD2 (0.41) | P2RX7DRD2DRD3PTPRCPTPN1 | |
| SCHEMBL7583803 | 0.79 | DRD2 (0.39) | P2RX7DRD2DRD3PTPRCPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114596-C | Biphenyl derivatives | EISAI CO LTD (JP) | 2003-07-16 | — | — | CN | claimed |
| CN-1117966-A | Biphenyl derivatives | EISAI CO LTD (JP) | 1996-03-06 | — | — | CN | claimed |
| CN-1114596-C | Biphenyl derivatives | EISAI CO LTD (JP) | 2003-07-16 | — | — | CN | disclosed |
| CN-1412661-A | Chinese character name code keyboard input method | LU YUSHAN (CN) | 2003-04-23 | — | — | CN | disclosed |
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| CN-1290700-A | Phenyl piperazine derivatives | EISAI LTD (JP) | 2001-04-11 | — | — | CN | disclosed |