Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.39 |
| ▸ | DRD3 | P35462 | 16/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590018 | 0.88 | DRD2 (0.41) | DRD2DRD3USP2ALDH1A1LMNA | |
| SCHEMBL7583792 | 0.85 | DRD2 (0.41) | DRD2DRD3USP2ALDH1A1LMNA | |
| SCHEMBL7587091 | 0.80 | P2RX7 (0.41) | DRD2DRD3LMNAP2RX7 | |
| SCHEMBL7585483 | 0.80 | P2RX7 (0.41) | DRD2DRD3LMNAHTTP2RX7 | |
| SCHEMBL7582092 | 0.79 | P2RX7 (0.40) | DRD2DRD3P2RX7PTPRCPTPN1 | |
| SCHEMBL7583781 | 0.79 | P2RX7 (0.51) | L3MBTL1P2RX7 | |
| SCHEMBL7583788 | 0.78 | P2RX7 (0.41) | DRD2DRD3LMNAP2RX7 | |
| SCHEMBL7582945 | 0.78 | P2RX7 (0.41) | DRD2DRD3LMNAP2RX7 | |
| SCHEMBL7589899 | 0.77 | NAAA (0.45) | DRD2DRD3ALDH1A1P2RX7 | |
| SCHEMBL27419636 | 0.76 | P2RX7 (0.40) | DRD2DRD3LMNAHTTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | claimed |