Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.42 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7577574 | 0.86 | MEN1 (0.48) | CA1CA2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6244215 | 0.82 | KCNQ2 (0.53) | CA1CA2KMT2AMEN1CYP1A2 | |
| SCHEMBL7573697 | 0.81 | CAMK2A (0.44) | CA1CA2KMT2AMEN1CYP1A2 | |
| SCHEMBL7576195 | 0.80 | TDP1 (0.51) | CA1CA2KMT2AMEN1S1PR3 | |
| SCHEMBL7583928 | 0.77 | TAS1R3 (0.51) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7574221 | 0.76 | ALDH1A1 (0.44) | CA1CA2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7584703 | 0.76 | NPC1 (0.53) | CA1CA2KMT2AMEN1S1PR3 | |
| SCHEMBL7575575 | 0.76 | KCNMA1 (0.54) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL7576888 | 0.76 | CLCN2 (0.50) | CA1CA2KMT2AMEN1CYP3A4 | |
| SCHEMBL360635 | 0.76 | CXCL8 (0.45) | CA1CA2KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |