Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7577574 | 0.88 | MEN1 (0.48) | TAS1R3TAS1R1CA1NPSR1ALDH1A1 | |
| SCHEMBL7577550 | 0.85 | PPARG (0.51) | TAS1R3TAS1R1KDM4EALDH1A1MAPT | |
| SCHEMBL6244215 | 0.83 | KCNQ2 (0.53) | CA1KDM4ENPSR1ALDH1A1LMNA | |
| SCHEMBL7575575 | 0.83 | KCNMA1 (0.54) | KDM4ENPSR1LMNAMAPTNPC1 | |
| SCHEMBL7574221 | 0.81 | ALDH1A1 (0.44) | TAS1R3TAS1R1CA1KDM4EALDH1A1 | |
| SCHEMBL3810329 | 0.80 | CA1 (0.46) | TAS1R3TAS1R1CA1CA14KDM4E | |
| SCHEMBL7573328 | 0.79 | ALDH1A1 (0.63) | KDM4ENPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL7582482 | 0.77 | CA1 (0.46) | CA1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL1696047 | 0.77 | MDM2 (0.48) | CA1KDM4EALDH1A1LMNAGAA | |
| SCHEMBL2639604 | 0.76 | NPC1 (0.54) | KDM4ENPSR1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |