Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL7584694 | 0.98 | P2RX7 (0.39) | P2RX7HTR2BNR1H2NR1H3MAPK1 | |
| SCHEMBL27419636 | 0.76 | P2RX7 (0.40) | P2RX7HTR2BMAPK1 | |
| SCHEMBL7587566 | 0.72 | P2RX7 (0.52) | P2RX7 | |
| Ethane SCHEMBL7590902 | 0.72 | ALDH1A1 (0.40) | P2RX7NR1H2NR1H3MAPK1 | |
| SCHEMBL7587657 | 0.71 | DPP4 (0.38) | P2RX7 | |
| SCHEMBL27430288 | 0.71 | P2RX7 (0.39) | P2RX7HTR2BNR1H2NR1H3 | |
| Methane SCHEMBL7585776 | 0.70 | HTR2A (0.33) | HTR2B | |
| Ethane SCHEMBL7582048 | 0.68 | HTR2A (0.33) | HTR2B | |
| SCHEMBL7587091 | 0.68 | P2RX7 (0.41) | P2RX7MAPK1 | |
| SCHEMBL7582092 | 0.67 | P2RX7 (0.40) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | claimed |