Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 10/20 | 0.35 |
| ▸ | DRD3 | P35462 | 10/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27419636 | 0.82 | P2RX7 (0.40) | DPP4P2RX7DRD2DRD3HTR7 | |
| SCHEMBL7581298 | 0.76 | HTR7 (0.35) | DPP4DRD2DRD3HTR7PDE4B | |
| SCHEMBL7587091 | 0.74 | P2RX7 (0.41) | DPP4P2RX7DRD2DRD3HTR7 | |
| SCHEMBL7582945 | 0.74 | P2RX7 (0.41) | DPP4P2RX7DRD2DRD3HTR7 | |
| SCHEMBL7582092 | 0.73 | P2RX7 (0.40) | DPP4P2RX7DRD2DRD3NAAA | |
| SCHEMBL7583788 | 0.72 | P2RX7 (0.41) | DPP4P2RX7DRD2DRD3HTR7 | |
| SCHEMBL7585483 | 0.72 | P2RX7 (0.41) | DPP4P2RX7DRD2DRD3LMNA | |
| Ethane SCHEMBL7584694 | 0.71 | P2RX7 (0.39) | P2RX7 | |
| Methane SCHEMBL7582930 | 0.71 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL7589899 | 0.71 | NAAA (0.45) | DPP4P2RX7DRD2DRD3PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | claimed |