Diclofop-Methyl

Diclofop-Methyl

SCHEMBL7582950

COC(=O)C(C)Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
TTR P02766 1/20 0.43
ALB P02768 1/20 0.43
THRB P10828 1/20 0.43
JMJD7 P0C870 1/20 0.42
MAPT P10636 4/20 0.40
LMNA P02545 4/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
ALOX12 P18054 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CCR6 P51684 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GAA P10253 1/20 0.40
ALDH1A1 P00352 3/20 0.39
HTT P42858 2/20 0.39
HPGD P15428 2/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diclofop-Methyl SCHEMBL7580344 0.88 TDP1 (0.56) KMT2AMEN1TDP1TTRJMJD7
Aclonifen SCHEMBL7586612 0.87 LMNA (0.45) KMT2AMEN1TDP1TTRALB
Diclofop-Methyl SCHEMBL7585389 0.86 MEN1 (0.58) KMT2AMEN1TDP1TTRALB
Acifluorfen SCHEMBL7587596 0.84 KMT2A (0.53) KMT2AMEN1TDP1TTRJMJD7
Clodinafop SCHEMBL7585781 0.84 KMT2A (0.41) KMT2AMEN1TDP1TTRALB
Oxyfluorfen SCHEMBL7583682 0.83 KMT2A (0.42) KMT2AMEN1TDP1TTRJMJD7
Diclofop-Methyl SCHEMBL7586776 0.82 JMJD7 (0.36) KMT2AMEN1TDP1TTRJMJD7
Fomesafen SCHEMBL7585215 0.81 KMT2A (0.44) KMT2AMEN1TDP1TTRJMJD7
Lactofen SCHEMBL7575654 0.80 KMT2A (0.44) KMT2AMEN1TDP1TTRJMJD7
Diclofop-Methyl SCHEMBL7588097 0.80 KMT2A (0.44) KMT2AMEN1TDP1TTRJMJD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885MEN1 4274/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.