SCHEMBL7583002

SCHEMBL7583002

O=C(C[C@H](NC(=O)OCc1ccccc1)C(=O)O)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 8/20 0.60
PPARA Q07869 3/20 0.55
PPARG P37231 1/20 0.55
CTSK P43235 3/20 0.54
TACR1 P25103 2/20 0.54
CTRB1 P17538 2/20 0.54
CTSL P07711 1/20 0.53
CTSB P07858 1/20 0.53
CTSS P25774 1/20 0.53
IDO1 P14902 1/20 0.53
TDO2 P48775 1/20 0.53
ALDH1A1 P00352 1/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2912586 1.00 CASP1 (0.60) CASP1PPARAPPARGCTSKTACR1
SCHEMBL2912589 1.00 CASP1 (0.60) CASP1PPARAPPARGCTSKTACR1
SCHEMBL7975561 0.92 CASP1 (0.55) CASP1PPARAPPARGCTSKCTSL
SCHEMBL3012469 0.91 CASP1 (0.56) CASP1PPARAPPARGCTSKTACR1
SCHEMBL755795 0.91 MMP9 (0.52) CASP1PPARAPPARGCTSKCTSL
SCHEMBL8116799 0.91 CASP1 (0.56) CASP1PPARAPPARGCTSKTACR1
SCHEMBL3012475 0.91 CASP1 (0.56) CASP1PPARAPPARGCTSKTACR1
SCHEMBL9312398 0.91 CASP1 (0.60) CASP1CTSKTACR1CTRB1CTSL
SCHEMBL8765627 0.91 CASP1 (0.60) CASP1CTSKTACR1CTRB1CTSL
SCHEMBL376886 0.89 CASP1 (0.67) CASP1PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116075499-A Novel dephosphorylated galectin derivatives with prodrug properties 指南针探路者有限公司 2023-05-05 CN claimed
EP-0284084-B1 INTENSELY SWEET L-ASPARTYL-3-(BICYCLOALKYL)-L-ALANINE ALKYL ESTERS THE COCA-COLA COMPANY (US) 1991-06-26 EP claimed
EP-0284084-A2 Intensely sweet L-aspartyl-3-(Bicycloalkyl)-L-alanine alkyl esters THE COCA-COLA COMPANY (US) 1988-09-28 EP claimed
JP-61291596-A None JP disclosed
JP-61291597-A None JP disclosed
JP-59163354-A None JP disclosed
JP-62067098-A None JP disclosed
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2026-01-22 US disclosed
EP-4615487-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES Merck Sharp & Dohme LLC (US) 2025-09-17 EP disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
WO-2024102633-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2024-05-16 WO disclosed
EP-0186173-A2 L-Aminodicarboxylic-(0-cycloalkyl)-L-aminocarboxylate alkyl esters, an edible composition containing same as sweeteners and a method for sweetening an edible composition GENERAL FOODS CORPORATION (US) 1986-07-02 EP disclosed
JP-S59163354-A TRIPEPTIDE DERIVATIVE AND SWEETENER CONTAINING THE SAME AJINOMOTO CO INC 1984-09-14 JP disclosed
US-4338346-A Non-nutritive sweetener THE PROCTER & GAMBLE COMPANY (US) 1982-07-06 US disclosed
EP-0013044-A1 L-aspartyl amide derivatives and their use as sweetening agents THE PROCTER & GAMBLE COMPANY (US) 1980-07-09 EP disclosed
US-4175084-A AND AN N-ACYL ASPARTIC ACID CARRIER, FOR PSYCHOLOGICAL DISORDERS, LEARNING ENHANCEMENT AND SLEEP INDUCTION SENTRALINSTITUTT FOR INDUSTRIELL FORSKNING (NO) 1979-11-20 US disclosed
US-4025551-A 3-Amino-N-substituted succinamic acids G. D. SEARLE & CO. (US) 1977-05-24 US disclosed
US-4011260-A 3-AMINO-N-SUBSTITUTED SUCCINAMIC ACIDS AND INTERMEDIATES THERETO G. D. SEARLE & CO. (US) 1977-03-08 US disclosed
US-3984417-A Method of producing active amino acid esters AJINOMOTO CO., INC. (JA) 1976-10-05 US disclosed
US-3959245-A SWEETENERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES INSR, GPR119, GLP1R CASP1 3852/4885PPARA 1213/4885PPARG 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.