SCHEMBL8765627

SCHEMBL8765627

O=C(CC(NC(=O)OCc1ccccc1)C(=O)OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 10/20 0.60
CTSK P43235 3/20 0.54
TACR1 P25103 2/20 0.54
CTRB1 P17538 2/20 0.54
CTSL P07711 1/20 0.53
CTSB P07858 1/20 0.53
CTSS P25774 1/20 0.53
IDO1 P14902 1/20 0.53
ALDH1A1 P00352 1/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9312398 1.00 CASP1 (0.60) CASP1CTSKTACR1CTRB1CTSL
SCHEMBL5405717 0.92 CASP1 (0.52) CASP1CTSKTACR1CTRB1CTSL
SCHEMBL25491977 0.91 MMP9 (0.52) CASP1CTSKTACR1CTSLCTSB
SCHEMBL7583002 0.91 CASP1 (0.60) CASP1CTSKTACR1CTRB1CTSL
SCHEMBL2912589 0.91 CASP1 (0.60) CASP1CTSKTACR1CTRB1CTSL
SCHEMBL2912586 0.91 CASP1 (0.60) CASP1CTSKTACR1CTRB1CTSL
SCHEMBL4280674 0.89 CASP1 (0.67) CASP1
SCHEMBL28709501 0.89 ALDH1A1 (0.53) CASP1TACR1CTRB1ALDH1A1
SCHEMBL4280669 0.89 CASP1 (0.67) CASP1
SCHEMBL14177313 0.89 ALDH1A1 (0.53) CASP1CTSKTACR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0624599-B1 Derivatives of mono (6-amino-desoxy)cyclodextrin substituted in position 6 with an alpha aminoacid group, process of their preparation and applications OREAL (FR) 1997-07-30 EP claimed
US-5631244-A PREPARATION OF INCLUSION COMPLEXES TO SOLUBILIZE COSMETIC AND DERMATOLOGICALLY ACTIVE MATERIALS L'OREAL (FR) 1997-05-20 US disclosed