Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7578510 | 0.88 | MEN1 (0.49) | BRD4HTTKMT2AALDH1A1GAA | |
| SCHEMBL2483409 | 0.83 | RAB9A (0.48) | HTTALDH1A1GAARAB9A | |
| Hydrochloric Acid SCHEMBL1695958 | 0.82 | RAB9A (0.47) | HTTALDH1A1GAALMNARAB9A | |
| SCHEMBL7584780 | 0.82 | KMT2A (0.46) | BRD4HTTKMT2AALDH1A1GAA | |
| SCHEMBL6824801 | 0.78 | BRD4 (0.60) | BRD4HTTKMT2AALDH1A1NPSR1 | |
| SCHEMBL2482091 | 0.77 | SMN1; SMN2 (0.53) | HTTKMT2AALDH1A1GAALMNA | |
| SCHEMBL7578887 | 0.76 | LMNA (0.50) | HTTKMT2AALDH1A1LMNATSHR | |
| SCHEMBL7574752 | 0.76 | NPSR1 (0.53) | HTTKMT2AALDH1A1GAANPSR1 | |
| SCHEMBL7583934 | 0.76 | ALDH1A1 (0.49) | HTTKMT2AALDH1A1GAANPSR1 | |
| SCHEMBL7583591 | 0.76 | TDP1 (0.50) | HTTKMT2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |