SCHEMBL7584032

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2133710	0.92	CES1 (0.81)	CES1CYP19A1ALDH1A1KMT2AMEN1
	SCHEMBL2474197	0.90	CES1 (1.00)	CES1CYP19A1ALDH1A1KMT2AMEN1
	SCHEMBL6554630	0.90	CES1 (1.00)	CES1CYP19A1ALDH1A1KMT2AMEN1
	SCHEMBL30209715	0.89	CES1 (0.76)	CES1CYP19A1ALDH1A1KMT2AMEN1
	SCHEMBL25132396	0.86	ALDH1A1 (0.74)	CES1ALDH1A1KMT2AMEN1PKM
	SCHEMBL15840711	0.86	ALDH1A1 (0.74)	CES1ALDH1A1KMT2AMEN1PKM
	SCHEMBL29562342	0.85	PGR (0.72)	CES1CYP19A1ALDH1A1KMT2AMEN1
	SCHEMBL9001182	0.85	KMT2A (1.00)	ALDH1A1KMT2AMEN1PKMIL1RN
	Phenyl(Phenylsulfonyl)Amine SCHEMBL114765	0.85	KEAP1 (1.00)	ALDH1A1KMT2AMEN1PKMIL1RN
	SCHEMBL25031372	0.85	KEAP1 (1.00)	ALDH1A1KMT2AMEN1PKMIL1RN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.