Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449686 | 0.83 | ALDH1A1 (0.40) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL9628663 | 0.81 | KMT2A (0.39) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6097183 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1SLC6A3ATM | |
| SCHEMBL9465235 | 0.73 | KMT2A (0.40) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL7590767 | 0.72 | PSIP1 (0.42) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6097178 | 0.70 | KMT2A (0.51) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL9180023 | 0.69 | SLC6A3 (0.34) | ALDH1A1RAB9AKMT2AMEN1GAA | |
| SCHEMBL8505555 | 0.69 | SLC6A3 (0.34) | ALDH1A1RAB9AKMT2AMEN1GAA | |
| SCHEMBL10911815 | 0.68 | KMT2A (0.41) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL9180026 | 0.68 | SLC6A3 (0.36) | ALDH1A1RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974580-B1 | Omega-cycloalkyl-prostaglandin E1 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-6235780-B1 | ANTIHISTAMINE; VISION DEFECTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0974580-A1 | Omega-cycloalkyl-prostaglandin E1 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-01-26 | — | — | EP | disclosed |