Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584043 | 0.72 | ALDH1A1 (0.39) | PSIP1RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL28763540 | 0.72 | PSIP1 (0.52) | PSIP1HSD11B1KMT2AALDH1A1TP53 | |
| SCHEMBL20087726 | 0.71 | HSD11B1 (0.49) | PSIP1HSD11B1RAB9ANPC1KMT2A | |
| SCHEMBL3868306 | 0.70 | PSIP1 (0.46) | PSIP1HSD11B1RAB9ANPC1KMT2A | |
| SCHEMBL29060741 | 0.69 | PSIP1 (0.48) | PSIP1HSD11B1ALDH1A1TP53HTT | |
| SCHEMBL2448610 | 0.68 | PSIP1 (0.56) | PSIP1HSD11B1RAB9ANPC1KMT2A | |
| SCHEMBL2443006 | 0.67 | PSIP1 (0.55) | PSIP1HSD11B1KMT2AALDH1A1TP53 | |
| SCHEMBL29060735 | 0.67 | FFAR4 (0.46) | PSIP1HSD11B1 | |
| SCHEMBL14362748 | 0.66 | HSD11B1 (0.50) | PSIP1HSD11B1KMT2AALDH1A1TP53 | |
| SCHEMBL7000851 | 0.66 | PSIP1 (0.48) | PSIP1HSD11B1RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974580-B1 | Omega-cycloalkyl-prostaglandin E1 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-6235780-B1 | ANTIHISTAMINE; VISION DEFECTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0974580-A1 | Omega-cycloalkyl-prostaglandin E1 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-01-26 | — | — | EP | disclosed |