Diclofop-Methyl

Diclofop-Methyl

SCHEMBL7584095

COC(=O)C(C)Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.38
MAPT P10636 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.38
HSP90AA1 P07900 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PKM P14618 1/20 0.37
HTT P42858 1/20 0.36
PPARG P37231 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
TTR P02766 1/20 0.35
PPOX P50336 1/20 0.35
PTGDR2 Q9Y5Y4 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
EGFR P00533 2/20 0.34
ERBB2 P04626 2/20 0.34
LMNA P02545 2/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mecoprop SCHEMBL7574069 0.90 TSHR (0.40) FFAR1MAPTMEN1KMT2AKDM4E
Lactofen SCHEMBL7575654 0.88 KMT2A (0.44) FFAR1MAPTMEN1KMT2AKDM4E
Acifluorfen SCHEMBL7587596 0.87 KMT2A (0.53) FFAR1MAPTMEN1KMT2AKDM4E
Clodinafop SCHEMBL7588909 0.87 FFAR1 (0.37) FFAR1MAPTMEN1KMT2AKDM4E
Diclofop-Methyl SCHEMBL7579170 0.87 FFAR1 (0.47) FFAR1MAPTMEN1KMT2AKDM4E
Diclofop-Methyl SCHEMBL7588097 0.84 KMT2A (0.44) MAPTMEN1KMT2AKDM4EHSP90AA1
Oxyfluorfen SCHEMBL7583682 0.84 KMT2A (0.42) FFAR1MAPTMEN1KMT2AKDM4E
Fomesafen SCHEMBL7585215 0.84 KMT2A (0.44) MAPTMEN1KMT2AKDM4EHSP90AA1
Diclofop-Methyl SCHEMBL7580344 0.81 TDP1 (0.56) FFAR1MAPTMEN1KMT2AKDM4E
Diclofop-Methyl SCHEMBL7589732 0.81 PKM (0.33) FFAR1MAPTMEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT FFAR1 4198/4885MAPT 1092/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.