Clodinafop

Clodinafop

SCHEMBL7588909

C[C@@H](Oc1ccc(Oc2ncc(Cl)cc2F)cc1)C(=O)O.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.37
PPARG P37231 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HSP90AA1 P07900 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PKM P14618 1/20 0.34
TTR P02766 1/20 0.34
PPOX P50336 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
PTGER4 P35408 1/20 0.33
CYP3A4 P08684 3/20 0.32
UGCG Q16739 3/20 0.32
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactofen SCHEMBL7576438 0.89 KMT2A (0.41) FFAR1PPARGL3MBTL1MEN1KMT2A
Clodinafop SCHEMBL7578270 0.89 FFAR1 (0.44) FFAR1L3MBTL1MEN1KMT2AMAPT
Diclofop-Methyl SCHEMBL7584095 0.87 FFAR1 (0.38) FFAR1PPARGL3MBTL1MEN1KMT2A
Mecoprop SCHEMBL7574069 0.87 TSHR (0.40) FFAR1PPARGL3MBTL1MEN1KMT2A
Oxyfluorfen SCHEMBL7583155 0.86 KMT2A (0.40) FFAR1PPARGL3MBTL1MEN1KMT2A
Clodinafop SCHEMBL7586462 0.86 KMT2A (0.41) FFAR1PPARGL3MBTL1MEN1KMT2A
Bifenox SCHEMBL7583525 0.82 TDP1 (0.49) PPARGL3MBTL1MEN1KMT2AMAPT
Clodinafop SCHEMBL7578870 0.81 PPARG (0.34) PPARGL3MBTL1MAPTPKMSMN1; SMN2
Clodinafop SCHEMBL7590509 0.80 PPARG (0.34) PPARGL3MBTL1PKM
Clodinafop SCHEMBL7586800 0.79 L3MBTL1 (0.35) FFAR1PPARGL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT FFAR1 4198/4885PPARG 777/4885L3MBTL1 2160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.