Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573344 | 0.85 | CXCR2 (0.56) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL7584758 | 0.83 | CXCR2 (0.56) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL7574996 | 0.81 | MEN1 (0.66) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL14398180 | 0.81 | CRHBP (0.48) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL2483532 | 0.80 | ULK1 (0.47) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL12071889 | 0.80 | ULK1 (0.47) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1695681 | 0.79 | ULK1 (0.46) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL7583883 | 0.79 | LMNA (0.58) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL7574185 | 0.77 | HPGD (0.57) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL7582132 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |