Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 3/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584758 | 0.89 | CXCR2 (0.56) | CXCR2CXCR1KCNMA1MAPTALDH1A1 | |
| SCHEMBL7585239 | 0.85 | KMT2A (0.57) | MAPTGAAALDH1A1HPGDMEN1 | |
| SCHEMBL7574996 | 0.82 | MEN1 (0.66) | KCNMA1MAPTGAAALDH1A1HPGD | |
| SCHEMBL14398180 | 0.82 | CRHBP (0.48) | CXCR2CXCR1MAPTGAAALDH1A1 | |
| SCHEMBL7583883 | 0.80 | LMNA (0.58) | KCNMA1MAPTGAAALDH1A1HPGD | |
| SCHEMBL11186123 | 0.79 | SMN1; SMN2 (0.59) | CXCR2CXCR1KCNMA1MAPTGAA | |
| SCHEMBL7574185 | 0.79 | HPGD (0.57) | CXCR2MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL7582132 | 0.78 | ALDH1A1 (0.57) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7575575 | 0.77 | KCNMA1 (0.54) | CXCR2KCNMA1MAPTHPGDMEN1 | |
| SCHEMBL7584383 | 0.77 | ALOX5 (0.50) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |