Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157261 | 0.84 | GAA (0.64) | ALDH1A1MEN1KMT2AGAAFKBP1A | |
| SCHEMBL7589116 | 0.83 | ALDH1A1 (0.92) | ALDH1A1HSD17B10L3MBTL1L3MBTL4L3MBTL3 | |
| SCHEMBL7588046 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HSD17B10MEN1KMT2AL3MBTL1 | |
| SCHEMBL7946476 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL3456792 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MEN1KMT2AL3MBTL1 | |
| SCHEMBL18706645 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HSD17B10L3MBTL1L3MBTL4L3MBTL3 | |
| SCHEMBL7946464 | 0.78 | FKBP1A (0.50) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL18706643 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HSD17B10L3MBTL1L3MBTL4L3MBTL3 | |
| SCHEMBL95898 | 0.77 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL13468136 | 0.77 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AFKBP1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006380-A1 | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them | MIGNANI SERGE (FR) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006380-A1 | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them | TNF, IL2, ZC3HAV1 | ALDH1A1 1762/4885HSD17B10 569/4885MEN1 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.