Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456792 | 0.87 | ALDH1A1 (0.58) | ALDH1A1FKBP1AMEN1KMT2AKDM4E | |
| SCHEMBL95898 | 0.86 | ALDH1A1 (0.60) | ALDH1A1FKBP1AMEN1KMT2AKDM4E | |
| SCHEMBL2157261 | 0.86 | GAA (0.64) | ALDH1A1FKBP1AMEN1KMT2AKDM4E | |
| SCHEMBL2157294 | 0.83 | ALDH1A1 (0.47) | ALDH1A1FKBP1AMEN1KMT2AKDM4E | |
| SCHEMBL21715104 | 0.83 | ALDH1A1 (0.63) | ALDH1A1FKBP1AMEN1KMT2AL3MBTL1 | |
| SCHEMBL13804351 | 0.81 | GAA (0.53) | KDM4EGAAHPGDL3MBTL1RECQL | |
| SCHEMBL7585371 | 0.81 | ALDH1A1 (0.65) | ALDH1A1FKBP1AMEN1KMT2AKDM4E | |
| SCHEMBL13468136 | 0.81 | ALDH1A1 (0.60) | ALDH1A1FKBP1AMEN1KMT2AHPGD | |
| SCHEMBL7960313 | 0.80 | TDP1 (0.61) | ALDH1A1KDM4EGAAHPGDL3MBTL1 | |
| SCHEMBL6291342 | 0.80 | FKBP1A (0.57) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194426-B1 | CONTROLLING TUMOR NECROSIS FACTOR | RHONA-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |