Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953700 | 0.82 | ALDH1A1 (0.50) | ALDH1A1PIK3CDTSHRGRM5PKM | |
| SCHEMBL7946476 | 0.79 | ALDH1A1 (0.56) | FKBP1AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2157294 | 0.78 | ALDH1A1 (0.47) | FKBP1AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2157261 | 0.78 | GAA (0.64) | FKBP1AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7585371 | 0.78 | ALDH1A1 (0.65) | FKBP1AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3456792 | 0.76 | ALDH1A1 (0.58) | FKBP1AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL31669039 | 0.76 | NR1D1 (0.65) | MEN1KMT2AALDH1A1PIK3CDPKM | |
| SCHEMBL28912695 | 0.76 | NR1D1 (0.65) | MEN1KMT2AALDH1A1PIK3CDPKM | |
| SCHEMBL24661351 | 0.75 | FKBP1A (0.65) | FKBP1AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL95898 | 0.75 | ALDH1A1 (0.60) | FKBP1AMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194426-B1 | CONTROLLING TUMOR NECROSIS FACTOR | RHONA-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |