Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585763 | 0.78 | REN (0.41) | MMP2MMP9MMP8RENTACR2 | |
| SCHEMBL7580182 | 0.65 | MAPT (0.44) | RENSMN1; SMN2ALDH1A1 | |
| SCHEMBL501988 | 0.64 | HRH3 (0.75) | CYP1A2SMN1; SMN2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL5233135 | 0.63 | MEN1 (0.58) | SMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL13107019 | 0.63 | NPC1 (0.50) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL23643889 | 0.62 | TDP1 (0.39) | CYP1A2SMN1; SMN2CYP2D6ALDH1A1 | |
| SCHEMBL5237806 | 0.62 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL5235455 | 0.60 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2D6CYP2C19 | |
| Oxalic Acid SCHEMBL48216 | 0.60 | LTA4H (0.53) | — | |
| SCHEMBL14027624 | 0.60 | CYP1A2 (0.44) | CYP1A2SMN1; SMN2CYP2D6CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |