Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | FLT3 | P36888 | 4/20 | 0.44 |
| ▸ | FLT1 | P17948 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157877 | 0.83 | NPBWR1 (0.49) | NPC1NPBWR1MCHR1L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL7159814 | 0.83 | NPBWR1 (0.48) | NPC1NPBWR1MCHR1L3MBTL1KMT2A | |
| SCHEMBL7587711 | 0.81 | MAPT (0.49) | NPC1NPBWR1MCHR1L3MBTL1KMT2A | |
| SCHEMBL7591765 | 0.80 | NPC1 (0.48) | NPC1NPBWR1MCHR1KDRFLT3 | |
| SCHEMBL7586158 | 0.80 | NPC1 (0.46) | NPC1NPBWR1MCHR1KDRFLT3 | |
| SCHEMBL7582824 | 0.77 | NPC1 (0.45) | NPC1NPBWR1MCHR1KDRFLT3 | |
| SCHEMBL7159289 | 0.73 | HPGD (0.60) | NPC1NPBWR1MCHR1MAPTPOLB | |
| SCHEMBL7838686 | 0.72 | HTR1A (0.55) | NPC1NPBWR1MCHR1MAPTMAPK1 | |
| SCHEMBL7591805 | 0.72 | ALDH1A1 (0.47) | NPC1NPBWR1MCHR1L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL7158449 | 0.72 | HPGD (0.58) | NPC1NPBWR1MCHR1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957099-B1 | Heterocyclic carboxamides | PFIZER PROD INC (US) | 2002-11-20 | — | — | EP | claimed |