Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158128 | 0.85 | NPBWR1 (0.48) | NPC1NPBWR1MCHR1SMYD2L3MBTL1 | |
| SCHEMBL7587711 | 0.83 | MAPT (0.49) | NPC1NPBWR1MCHR1L3MBTL1MEN1 | |
| SCHEMBL7586013 | 0.80 | NPC1 (0.47) | NPC1NPBWR1MCHR1L3MBTL1MEN1 | |
| SCHEMBL7591765 | 0.79 | NPC1 (0.48) | NPC1NPBWR1MCHR1L3MBTL1MEN1 | |
| SCHEMBL7582824 | 0.78 | NPC1 (0.45) | NPC1NPBWR1MCHR1SMYD2L3MBTL1 | |
| SCHEMBL7591805 | 0.74 | ALDH1A1 (0.47) | NPC1NPBWR1MCHR1SMYD2L3MBTL1 | |
| SCHEMBL7159289 | 0.74 | HPGD (0.60) | NPC1NPBWR1MCHR1USP2MAPK1 | |
| Hydrochloric Acid SCHEMBL7960841 | 0.73 | F10 (0.49) | NPC1NPBWR1MCHR1SMYD2L3MBTL1 | |
| SCHEMBL7838686 | 0.73 | HTR1A (0.55) | NPC1NPBWR1MCHR1MAPK1MAPT | |
| Hydrochloric Acid SCHEMBL7158449 | 0.72 | HPGD (0.58) | NPC1NPBWR1MCHR1USP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957099-B1 | Heterocyclic carboxamides | PFIZER PROD INC (US) | 2002-11-20 | — | — | EP | claimed |