Clodinafop

Clodinafop

SCHEMBL7586800

C[C@@H](Oc1ccc(Oc2ncc(Cl)cc2F)cc1)C(=O)O.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.35
KMT2A Q03164 3/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
LMNA P02545 2/20 0.35
ALOX12 P18054 2/20 0.35
CCR6 P51684 1/20 0.35
PPARG P37231 4/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
GAA P10253 1/20 0.33
PKM P14618 1/20 0.32
LTA4H P09960 2/20 0.32
KCNH2 Q12809 1/20 0.32
JMJD7 P0C870 1/20 0.32
KDM4E B2RXH2 2/20 0.32
HSP90AA1 P07900 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clodinafop SCHEMBL7578921 0.87 SMN1; SMN2 (0.38) L3MBTL1KMT2AMEN1LMNALTA4H
Mecoprop SCHEMBL7578934 0.87 KMT2A (0.41) L3MBTL1KMT2AMAPTMEN1NPSR1
Diclofop-Methyl SCHEMBL7586776 0.86 JMJD7 (0.36) L3MBTL1KMT2AMAPTMEN1NPSR1
Oxyfluorfen SCHEMBL7583155 0.84 KMT2A (0.40) L3MBTL1KMT2AMAPTMEN1NPSR1
Clodinafop SCHEMBL7585781 0.84 KMT2A (0.41) L3MBTL1KMT2AMAPTMEN1NPSR1
Clodinafop SCHEMBL7586462 0.81 KMT2A (0.41) L3MBTL1KMT2AMAPTMEN1NPSR1
Lactofen SCHEMBL7576438 0.81 KMT2A (0.41) L3MBTL1KMT2AMAPTMEN1NPSR1
Clodinafop SCHEMBL7588909 0.79 FFAR1 (0.37) L3MBTL1KMT2AMAPTMEN1NPSR1
Bifenox SCHEMBL7583525 0.79 TDP1 (0.49) L3MBTL1KMT2AMAPTMEN1NPSR1
SCHEMBL7585729 0.76 MEN1 (0.38) KMT2AMAPTMEN1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT L3MBTL1 2160/4885KMT2A 2099/4885MAPT 1092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.