SCHEMBL7585729

SCHEMBL7585729

C[C@@H](Oc1ccc(Oc2ccc(C#N)cc2F)cc1)C(=O)O.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
TTR P02766 1/20 0.38
PPOX P50336 1/20 0.38
PTGDR2 Q9Y5Y4 2/20 0.37
MERTK Q12866 1/20 0.36
GABRP O00591 4/20 0.36
GABRD O14764 4/20 0.36
GABRA1 P14867 4/20 0.36
GABRB1 P18505 4/20 0.36
GABRG2 P18507 4/20 0.36
GABRB3 P28472 4/20 0.36
GABRA5 P31644 4/20 0.36
GABRA3 P34903 4/20 0.36
GABRA2 P47869 4/20 0.36
GABRB2 P47870 4/20 0.36
GABRA4 P48169 4/20 0.36
GABRE P78334 4/20 0.36
GABRA6 Q16445 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clodinafop SCHEMBL7578921 0.84 SMN1; SMN2 (0.38) MEN1KMT2ATDP1TTRPPOX
Fluazifop SCHEMBL7583299 0.82 RAB9A (0.47) MEN1KMT2ATDP1TTRPPOX
Diclofop-Methyl SCHEMBL7587639 0.80 TDP1 (0.43) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL7586913 0.80 TDP1 (0.65) MEN1KMT2ATDP1TTRPPOX
Mecoprop SCHEMBL7581550 0.79 TSHR (0.48) MEN1KMT2ATDP1TTRPPOX
Quizalofop SCHEMBL7581249 0.78 LMNA (0.47) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL7587520 0.78 MEN1 (0.49) MEN1KMT2ATDP1TTRPPOX
Fenoxaprop SCHEMBL7588818 0.78 PPARG (0.34) MEN1KMT2ATDP1TTRPPOX
Clodinafop SCHEMBL7586800 0.76 L3MBTL1 (0.35) MEN1KMT2ATDP1FFAR1SMN1; SMN2
SCHEMBL12668049 0.74 GAA (0.53) TDP1PTGDR2FFAR1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.