SCHEMBL758699

SCHEMBL758699

C=CCn1sc2ccccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 5/20 1.00
FAAH O00519 2/20 0.53
MGLL Q99685 2/20 0.53
KAT2A Q92830 1/20 0.51
KAT2B Q92831 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16916878 0.91 CASP3 (0.83) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL3142138 0.80 CASP3 (0.67) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL29679341 0.80 CASP3 (0.67) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL11278746 0.80 CASP3 (0.74) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL17948304 0.80 CASP3 (0.72) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL9886469 0.77 CASP3 (0.61) CASP3KAT2AKAT2B
SCHEMBL24836231 0.77 FAAH (0.81) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL3143600 0.77 CASP3 (1.00) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL24836229 0.77 FAAH (0.76) CASP3FAAHMGLLKAT2AKAT2B
SCHEMBL2963555 0.77 CASP3 (0.68) CASP3FAAHMGLLKAT2AKAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368713-A Antibacterial injection molding for automotive interior and preparation method thereof 扬州维辰汽车电子有限公司 2022-11-22 CN claimed
CN-113914008-A Antibacterial fiber fabric and preparation method thereof 常熟市欣鑫经纬编有限公司 2022-01-11 CN claimed
CN-111574472-A Synthesis method of 1, 2-benzisothiazolin-3-ketone compound 大连百傲化学股份有限公司 2020-08-25 CN claimed
EP-2925734-B1 METHOD FOR PREPARATION OF 2-ALKYL-1,2-BENZISOTHIAZOLIN-3-ONES ROHM & HAAS (US) 2016-10-05 EP claimed
EP-2157862-B1 BIOCIDE COMPOSITION CONTAINING GLUTARALDEHYDE AND AT LEAST ONE ISOTHIAZOLINONE THOR GMBH (DE) 2016-03-30 EP claimed
US-20150291541-A1 METHOD FOR PREPARATION OF 2-ALKYL-1,2-BENZISOTHIAZOLIN-3-ONES DDP SPECIALTY ELECTRONIC MATERIALS US 8, LLC 2015-10-15 US claimed
US-9139540-B1 Method for preparation of 2-alkyl-1,2-benzisothiazolin-3-ones DOW GLOBAL TECHNOLOGIES LLC (US) 2015-09-22 US claimed
EP-2514309-B1 Biocidal compound as additive for metal processing fluids THOR GMBH (DE) 2015-07-29 EP claimed
EP-2514309-A1 Biocidal compound as additive for metal processing fluids THOR GmbH (DE) 2012-10-24 EP claimed
US-20100260813-A1 Rodenticide Mixture BASF SE (DE) 2010-10-14 US claimed
EP-2194790-A2 RODENTICIDE MIXTURE Basf Se (DE) 2010-06-16 EP claimed
US-20100099793-A1 Gluing and Sealing Compounds Having Antimicrobial Properties THOR GMBH (DE) 2010-04-22 US claimed
EP-2106418-A1 GLUING AND SEALING COMPOUNDS HAVING ANTIMICROBIAL PROPERTIES THOR GmbH (DE) 2009-10-07 EP claimed
WO-2009047175-A2 RODENTICIDE MIXTURE BASF SE (DE) 2009-04-16 WO claimed
WO-2008080963-A1 GLUING AND SEALING COMPOUNDS HAVING ANTIMICROBIAL PROPERTIES THOR GMBH (DE) 2008-07-10 WO claimed
WO-2008000797-A2 ANTIMICROBIAL MICROPARTICLES THOR GMBH (DE) 2008-01-03 WO claimed
WO-2007131735-A2 CONCENTRATE FOR FILM PRESERVATION ISP INVESTMENTS INC. (US) 2007-11-22 WO claimed
EP-0475123-B1 Use of 2-n-alkyl-1,2-benzisothiazolin-3-ones as technical microbiocides RIEDEL DE HAEN AG (DE) 1995-01-04 EP claimed
JP-58096005-A None JP disclosed
EP-0018100-A2 Substituted aromatic biologically active compound, a process for its preparation and its use as biocide IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-10-29 EP disclosed